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There are several matches for 'HSP90 family protein'.
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2266 matches
showing page 1 of 114
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organism
protein
1)
Homo sapiens
TTI2 - TELO2-interacting
protein
2; Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize
protein
levels of the phosphatidylinositol 3-kinase-related
protein
kinase (PIKK)
family
proteins
. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and
HSP90
may participate in the proper folding of newly synthesized PIKKs.
[a.k.a. ENST00000613904, chromosome 8 open reading frame 41, TTI2-203]
2)
Homo sapiens
TELO2 - Telomere length regulation
protein
TEL2 homolog; Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize
protein
levels of the phosphatidylinositol 3-kinase-related
protein
kinase (PIKK)
family
proteins
. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and
HSP90
may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, wh [...]
[a.k.a. XP_011521077.1, ENST00000497339, NP_001338775]
3)
Homo sapiens
TTI1 - TELO2-interacting
protein
1 homolog; Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize
protein
levels of the phosphatidylinositol 3-kinase-related
protein
kinase (PIKK)
family
proteins
. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and
HSP90
may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate [...]
[a.k.a. ENST00000473288, ENST00000373448, XR_244159.4]
4)
Mus musculus
Tti2 - TELO2-interacting
protein
2; Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize
protein
levels of the phosphatidylinositol 3-kinase-related
protein
kinase (PIKK)
family
proteins
. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and
HSP90
may participate in the proper folding of newly synthesized PIKKs (By similarity); Belongs to the TTI2
family
.
[a.k.a. NP_001186917.1, ENSMUST00000209986, ENSMUSG00000031577]
5)
Mus musculus
Tti1 - TELO2-interacting
protein
1 homolog; Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize
protein
levels of the phosphatidylinositol 3-kinase-related
protein
kinase (PIKK)
family
proteins
. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and
HSP90
may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate [...]
[a.k.a. NM_029282, MGI:1922675, ENSMUST00000109522]
6)
Mus musculus
Telo2 - Telomere length regulation
protein
TEL2 homolog; Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize
protein
levels of the phosphatidylinositol 3-kinase-related
protein
kinase (PIKK)
family
proteins
. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and
HSP90
may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, wh [...]
[a.k.a. Q3UID7, ENSMUSG00000024170, NP_001157133]
7)
Mus musculus
Cdc37l1 -
Hsp90
co-chaperone Cdc37-like 1; Co-chaperone that binds to numerous
proteins
and promotes their interaction with Hsp70 and
Hsp90
; Belongs to the CDC37
family
.
[a.k.a. XP_006527334, ENSMUST00000224092, UPI00000E98F8]
8)
Mus musculus
Ahsa2 - Activator of 90 kDa heat shock
protein
ATPase homolog 2; Co-chaperone that stimulates
HSP90
ATPase activity. Belongs to the AHA1
family
.
[a.k.a. BAE23240.1, Ahsa2-204, UPI00001E6FDC]
9)
Mus musculus
Ptges3 - Prostaglandin E synthase 3; Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha
proteins
hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the
HSP90
pathway; Belongs to the p23/wos2
family
.
[a.k.a. AAH85264.1, BAC36854.1, cPGES]
10)
Mus musculus
Pdcl3 - Phosducin-like
protein
3; Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, increasing its abundance by inhibiting its ubiquitination and degradation. Inhibits the folding activity of the chaperonin-containing T-complex (CCT) which leads to inhibition of cytoskeletal actin folding (By similarity). Acts as a chaperone during heat shock alongside
HSP90
and HSP40/70 chaperone complexes (By similarity). Modulates the activation of caspases during apoptosis (By similarity); Belongs to the phosducin
family
.
[a.k.a. AK168509, ENSMUSP00000027247, ENSMUST00000194552]
11)
Drosophila melanogaster
Trap1 - Trap1, isoform A; Trap1 (Trap1) encodes a mitochondrial chaperone
protein
of the heat shock
protein
(
HSP90
)
family
. It shows an ATPase activity and is involved in neurodegeneration associated with mitochondrial dysfunction.
[a.k.a. FBgn0026761, Trap1-PA, Trap1-PB]
12)
Drosophila melanogaster
Gp93 - Glycoprotein 93 (Gp93) encodes a heat shock
protein
Hsp90
family
member that is involved in midgut development.
[a.k.a. FBgn0039562, Gp93-PA, dme:Dmel_CG5520]
13)
Drosophila melanogaster
p23 - Uncharacterized
protein
CG16817; prostaglandin-E synthase activity;
Hsp90
protein
binding; chaperone binding. It is involved in the biological process described with:
protein
folding; positive regulation of small RNA loading onto RISC; chaperone-mediated
protein
complex assembly; Belongs to the p23/wos2
family
.
[a.k.a. FBgn0037728, p23-PB, p23-PA]
14)
Drosophila melanogaster
Dpit47 - DNA polymerase interacting tpr containing
protein
of 47kD (Dpit47) encodes a TPR motif containing
protein
that appears to act as a co-chaperone
protein
in the
Hsp90
pathway; Belongs to the TTC4
family
.
[a.k.a. FBgn0266518, Dpit47-PB, Dpit47-PA]
15)
Saccharomyces cerevisiae
SBA1 - Co-chaperone
protein
SBA1; Co-chaperone that binds and regulates
Hsp90
family
chaperones; plays a role in determining prion variants; important for pp60v-src activity in yeast; homologous to the mammalian p23
proteins
, and like p23 can regulate telomerase activity;
protein
abundance increases in response to DNA replication stress; Belongs to the p23/wos2
family
.
[a.k.a. YKL117W, 853743, AAB22000.1]
16)
Saccharomyces cerevisiae
YDJ1 - Mitochondrial
protein
import
protein
MAS5; Type I HSP40 co-chaperone; involved in regulation of
HSP90
and HSP70 functions; acts as an adaptor that helps Rsp5p recognize cytosolic misfolded
proteins
for ubiquitination after heat shock; critical for determining cell size at Start as a function of growth rate; involved in
protein
translocation across membranes; member of the DnaJ
family
; chimeric
protein
in which human p58IPK J domain replaces yeast Ydj1p J domain can complement yeast ydj1 mutant.
[a.k.a. YNL064C, S000005008, 1XAO]
17)
Saccharomyces cerevisiae
HCH1 -
Hsp90
co-chaperone HCH1; Heat shock
protein
regulator; binds to Hsp90p and may stimulate ATPase activity; originally identified as a high-copy number suppressor of a
HSP90
loss-of-function mutation; role in regulating
Hsp90
inhibitor drug sensitivity; GFP-fusion
protein
localizes to the cytoplasm and nucleus;
protein
abundance increases in response to DNA replication stress; Belongs to the AHA1
family
.
[a.k.a. YNL281W, S000005225, NP_014118.1]
18)
Saccharomyces cerevisiae
SGT1 - Cochaperone
protein
; regulates activity of adenylyl cyclase Cyr1p; involved in kinetochore complex assembly; associates with the SCF (Skp1p/Cdc53p/F box
protein
) ubiquitin ligase complex; acts as a linker between Skp1p and
HSP90
complexes;
protein
abundance increases in response to DNA replication stress; Belongs to the SGT1
family
.
[a.k.a. YOR057W, L000004087, Q08446]
19)
Saccharomyces cerevisiae
PPT1 -
Protein
serine/threonine phosphatase; regulates
Hsp90
chaperone by affecting its ATPase and cochaperone binding activities; has similarity to human phosphatase PP5; present in both the nucleus and cytoplasm; expressed during logarithmic growth; Belongs to the PPP phosphatase
family
. PP-5 (PP-T) subfamily.
[a.k.a. YGR123C, 3.1.3.16, UPI0000053298]
20)
Saccharomyces cerevisiae
AHA1 -
Hsp90
co-chaperone AHA1; Co-chaperone that binds Hsp82p and activates its ATPase activity; plays a role in determining prion variants; similar to Hch1p; expression is regulated by stresses such as heat shock;
protein
abundance increases in response to DNA replication stress; Belongs to the AHA1
family
.
[a.k.a. YDR214W, 4932.YDR214W, S000002622]
2266 matches
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